The BeadBug 6 utilizes a three dimensional shaking motion to disrupt samples. This
motion, when combined with beads of the appropriate size and material, causes
high velocity impacts with the sample and is an extremely fast and efficient
method for releasing cellular contents, including nucleic acids and proteins.
Many different sample types, from cells in culture to organ tissues and bone
can be homogenized in the BeadBug 6, most within 45 seconds. Programming
the unit is very simple – just set the speed, time, number of cycles and pause
between cycles, then press start. For convenience, the last programmed
parameters remain in memory for repeated runs.
Sealed tubes prevent cross contamination in the BeadBug 6. Samples are
simply loaded into the tubes along with the beads and placed in the unit for
processing. After homogenization, tubes are spun briefly in a centrifuge, and
the lysate removed with a pipette.