Also known as crossflow filtration, TFF is used to clarify process fluids including cell culture media, and to concentrate and buffer exchange macromolecules such as proteins, viruses, nucleic acids, and nanoparticles. Although TFF originated in commercial manufacturing, it is increasingly relevant and popular in research laboratories where larger sample (feed) volumes need to be processed.
Groundbreaking Vivaflow® cassettes from Sartorius simplify TFF for researchers who need to prioritize efficiency over complexity. Available in reusable and brand-new single use formats with our most comprehensive selection of membrane materials and MWCOs, you can always find the right solution for effortless concentration and buffer exchange of any molecule from 0.1 to 5 L feed volumes.
